Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Zinc finger protein 263 (557-607) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:1000-2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ZNF263 |
Gene ID: |
10127 |
Uniprot ID: |
ZN263_HUMAN |
Immunogen Region: |
557-607 |
Specificity: |
This antibody detects endogenous levels of human ZN263 |
Immunogen: |
Synthesized peptide derived from human ZN263 AA range: 557-607 |
Post Translational Modifications | Ubiquitinated, leading to proteasomal degradation. |
Function | Transcription factor that binds to the consensus sequence 5'-TCCTCCC-3' and acts as a transcriptional repressor. Binds to the promoter region of SIX3 and recruits other proteins involved in chromatin modification and transcriptional corepression, resulting in methylation of the promoter and transcriptional repression. Acts as transcriptional repressor of HS3ST1 and HS3ST3A1 via binding to gene promoter regions. |
Protein Name | Zinc Finger Protein 263Zinc Finger Protein Fpm315Zinc Finger Protein With Krab And Scan Domains 12 |
Database Links | Reactome: R-HSA-212436 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Zinc Finger Protein 263 antibodyAnti-Zinc Finger Protein Fpm315 antibodyAnti-Zinc Finger Protein With Krab And Scan Domains 12 antibodyAnti-ZNF263 antibodyAnti-FPM315 antibodyAnti-ZKSCAN12 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance