Anti-ZNF263 antibody (557-607) (STJA0006562)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human ZN263 AA range: 557-607
General Information
| Short Description | Rabbit polyclonal anti-Zinc finger protein 263 (557-607) for use in WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ZNF263 |
| Gene ID | 10127 |
| Uniprot ID | ZN263_HUMAN |
| Immunogen | Synthesized peptide derived from human ZN263 AA range: 557-607 |
| Immunogen Region | 557-607 |
| Specificity | This antibody detects endogenous levels of human ZN263 |
Additional Info
| Post Translational Modifications | Ubiquitinated, leading to proteasomal degradation. |
| Function | Transcription factor that binds to the consensus sequence 5'-TCCTCCC-3' and acts as a transcriptional repressor. Binds to the promoter region of SIX3 and recruits other proteins involved in chromatin modification and transcriptional corepression, resulting in methylation of the promoter and transcriptional repression. Acts as a transcriptional repressor of HS3ST1 and HS3ST3A1 via binding to gene promoter regions. |
| Protein Name | Zinc Finger Protein 263Zinc Finger Protein Fpm315Zinc Finger Protein With Krab And Scan Domains 12 |
| Database Links | Reactome: R-HSA-212436 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Zinc Finger Protein 263 antibodyAnti-Zinc Finger Protein Fpm315 antibodyAnti-Zinc Finger Protein With Krab And Scan Domains 12 antibodyAnti-ZNF263 antibodyAnti-FPM315 antibodyAnti-ZKSCAN12 antibody |
Information sourced from Uniprot.org