Anti-ZNF106 antibody (1833-1882 aa) (STJ96306)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human ZFP106 at the amino acid range 1833-1882
General Information
| Short Description | Rabbit polyclonal anti-Zinc finger protein 106 (1833-1882 aa) for use in WB and ELISA in Human, Mouse and Monkey samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Monkey |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ZNF106 |
| Gene ID | 64397 |
| Uniprot ID | ZN106_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human ZFP106 at the amino acid range 1833-1882 |
| Immunogen Region | 1833-1882 aa |
| Specificity | ZFP106 Polyclonal Antibody detects endogenous levels of ZFP106 protein. |
Additional Info
| Function | RNA-binding protein. Specifically binds to 5'-GGGGCC-3' sequence repeats in RNA. Essential for maintenance of peripheral motor neuron and skeletal muscle function. Required for normal expression and/or alternative splicing of a number of genes in spinal cord and skeletal muscle, including the neurite outgrowth inhibitor RTN4. Also contributes to normal mitochondrial respiratory function in motor neurons, via an unknown mechanism. |
| Protein Name | Zinc Finger Protein 106Zfp-106Zinc Finger Protein 474 |
| Database Links | |
| Cellular Localisation | NucleusNucleolusNucleus SpeckleColocalizes With Rbm39 In Nuclear SpecklesInhibition Of Rna SynthesisOr Overexpression Of Knop1Induces Translocation From Nuclear Speckles To The Nucleolus |
| Alternative Antibody Names | Anti-Zinc Finger Protein 106 antibodyAnti-Zfp-106 antibodyAnti-Zinc Finger Protein 474 antibodyAnti-ZNF106 antibodyAnti-SH3BP3 antibodyAnti-ZFP106 antibodyAnti-ZNF474 antibody |
Information sourced from Uniprot.org