• Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using ZMY11 Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-ZMYND11 antibody (111-160 aa) (STJ91902)

SKU:
STJ91902

$62.10 - $305.10
Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Zinc finger MYND domain-containing protein 11 (111-160 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ZMYND11
Gene ID: 10771
Uniprot ID: ZMY11_HUMAN
Immunogen Region: 111-160 aa
Specificity: BS69 Polyclonal Antibody detects endogenous levels of BS69 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human ZMY11 at the amino acid range 111-160
Post Translational Modifications Sumoylated following its interaction with PIAS1 and UBE2I. Ubiquitinated, leading to proteasomal degradation.
Function Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Binds non-specifically to dsDNA. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth. (Microbial infection) Inhibits Epstein-Barr virus EBNA2-mediated transcriptional activation and host cell proliferation, through direct interaction.
Protein Name Zinc Finger Mynd Domain-Containing Protein 11
Adenovirus 5 E1a-Binding Protein
Bone Morphogenetic Protein Receptor-Associated Molecule 1
Protein Bs69
Cellular Localisation Nucleus
Chromosome
Associates With Chromatin And Mitotic Chromosomes
Alternative Antibody Names Anti-Zinc Finger Mynd Domain-Containing Protein 11 antibody
Anti-Adenovirus 5 E1a-Binding Protein antibody
Anti-Bone Morphogenetic Protein Receptor-Associated Molecule 1 antibody
Anti-Protein Bs69 antibody
Anti-ZMYND11 antibody
Anti-BRAM1 antibody
Anti-BS69 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance