Anti-ZMYND11 antibody (111-160 aa) (STJ91902)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human ZMY11 at the amino acid range 111-160
General Information
| Short Description | Rabbit polyclonal anti-Zinc finger MYND domain-containing protein 11 (111-160 aa) for use in IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ZMYND11 |
| Gene ID | 10771 |
| Uniprot ID | ZMY11_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human ZMY11 at the amino acid range 111-160 |
| Immunogen Region | 111-160 aa |
| Specificity | BS69 Polyclonal Antibody detects endogenous levels of BS69 protein. |
Additional Info
| Post Translational Modifications | Sumoylated following its interaction with PIAS1 and UBE2I. Ubiquitinated, leading to proteasomal degradation. |
| Function | Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Binds non-specifically to dsDNA. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth. (Microbial infection) Inhibits Epstein-Barr virus EBNA2-mediated transcriptional activation and host cell proliferation, through direct interaction. |
| Protein Name | Zinc Finger Mynd Domain-Containing Protein 11Adenovirus 5 E1a-Binding ProteinBone Morphogenetic Protein Receptor-Associated Molecule 1Protein Bs69 |
| Database Links | |
| Cellular Localisation | NucleusChromosomeAssociates With Chromatin And Mitotic Chromosomes |
| Alternative Antibody Names | Anti-Zinc Finger Mynd Domain-Containing Protein 11 antibodyAnti-Adenovirus 5 E1a-Binding Protein antibodyAnti-Bone Morphogenetic Protein Receptor-Associated Molecule 1 antibodyAnti-Protein Bs69 antibodyAnti-ZMYND11 antibodyAnti-BRAM1 antibodyAnti-BS69 antibody |
Information sourced from Uniprot.org