| Host: |
Rabbit |
| Applications: |
IHC/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Zinc Finger Protein With Krab And Scan Domains 3 is suitable for use in Immunohistochemistry and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Purification: |
Antigen affinity purification |
| Concentration: |
1 mg/mL |
| Dilution Range: |
IHC 1:40-1:250 |
| Storage Instruction: |
Store at-20°C for long term, and avoid freeze-thaw cycles. |
| Function | Transcriptional factor that binds to the consensus sequence 5'-GTAGAGTGGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migration in various tumors and myelomas. |
| Protein Name | Zinc Finger Protein With Krab And Scan Domains 3Zinc Finger And Scan Domain-Containing Protein 13Zinc Finger Protein 306Zinc Finger Protein 309Zinc Finger Protein 47 HomologZf47Zfp-47 |
| Database Links | Reactome: R-HSA-212436 |
| Cellular Localisation | NucleusCytoplasmMainly Localizes In The NucleusUnder Starvation Conditions Translocates To The CytoplasmAllowing Expression Of Target Genes Involved In Autophagy And Lysosome Biogenesis/Function |
| Alternative Antibody Names | Anti-Zinc Finger Protein With Krab And Scan Domains 3 antibodyAnti-Zinc Finger And Scan Domain-Containing Protein 13 antibodyAnti-Zinc Finger Protein 306 antibodyAnti-Zinc Finger Protein 309 antibodyAnti-Zinc Finger Protein 47 Homolog antibodyAnti-Zf47 antibodyAnti-Zfp-47 antibodyAnti-ZKSCAN3 antibodyAnti-ZFP47 antibodyAnti-ZNF306 antibodyAnti-ZNF309 antibodyAnti-ZSCAN13 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
