Anti-ZKSCAN3 antibody (STJA0004719)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenFusion protein of human ZKSCAN3
General Information
| Short Description | Rabbit polyclonal antibody anti-Zinc Finger Protein With Krab And Scan Domains 3 is suitable for use in Immunohistochemistry and ELISA research applications. |
| Applications | IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity purification |
| Dilution Range | IHC 1:40-1:250 |
| Formulation | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Storage Instruction | Store at-20°C for long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | ZKSCAN3 |
| Gene ID | 80317 |
| Uniprot ID | ZKSC3_HUMAN |
| Immunogen | Fusion protein of human ZKSCAN3 |
Additional Info
| Function | Transcriptional factor that binds to the consensus sequence 5'-GTAGAGTGGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migration in various tumors and myelomas. |
| Protein Name | Zinc Finger Protein With Krab And Scan Domains 3Zinc Finger And Scan Domain-Containing Protein 13Zinc Finger Protein 306Zinc Finger Protein 309Zinc Finger Protein 47 HomologZf47Zfp-47 |
| Database Links | Reactome: R-HSA-212436 |
| Cellular Localisation | NucleusCytoplasmMainly Localizes In The NucleusUnder Starvation Conditions Translocates To The CytoplasmAllowing Expression Of Target Genes Involved In Autophagy And Lysosome Biogenesis/Function |
| Alternative Antibody Names | Anti-Zinc Finger Protein With Krab And Scan Domains 3 antibodyAnti-Zinc Finger And Scan Domain-Containing Protein 13 antibodyAnti-Zinc Finger Protein 306 antibodyAnti-Zinc Finger Protein 309 antibodyAnti-Zinc Finger Protein 47 Homolog antibodyAnti-Zf47 antibodyAnti-Zfp-47 antibodyAnti-ZKSCAN3 antibodyAnti-ZFP47 antibodyAnti-ZNF306 antibodyAnti-ZNF309 antibodyAnti-ZSCAN13 antibody |
Information sourced from Uniprot.org