Anti-Zip12 antibody (1-100) (STJ118446)

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STJ118446
€140.63 - €655.63
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SLC39A12
Gene ID: 221074
Uniprot ID: S39AC_HUMAN
Immunogen Region: 1-100
Specificity: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SLC39A12 (NP_001138667.1).
Immunogen Sequence: MCFRTKLSVSWVPLFLLLSR VFSTETDKPSAQDSRSRGSS GQPADLLQVLSAGDHPPHNH SRSLIKTLLEKTGCPRRRNG MQGDCNLCFEPDALLLIAGG
Tissue Specificity Expressed in brain and eye.
Function Uniporter that promotes Zn(2+) import from the extracellular space to the cytoplasm across the cell membrane. The transport activity is temperature dependent. May play a role in neurulation and neurite extension. May play a key role in maintaining intracellular zinc content at levels that reduce the inhibitory effects of rises in oxidative stress on spermatogonia and spermatozoa viability during spermatogenesis.
Protein Name Zinc Transporter Zip12
Liv-1 Subfamily Of Zip Zinc Transporter 8
Lzt-Hs8
Solute Carrier Family 39 Member 12
Zrt- And Irt-Like Protein 12
Zip-12
Cellular Localisation Membrane
Multi-Pass Membrane Protein
At Low Zn(2+) Extracellular Concentration
Is Redistributed From The Perinuclear Space To The Cytoplasm And Plasma Membrane
Alternative Antibody Names Anti-Zinc Transporter Zip12 antibody
Anti-Liv-1 Subfamily Of Zip Zinc Transporter 8 antibody
Anti-Lzt-Hs8 antibody
Anti-Solute Carrier Family 39 Member 12 antibody
Anti-Zrt- And Irt-Like Protein 12 antibody
Anti-Zip-12 antibody
Anti-SLC39A12 antibody
Anti-ZIP12 antibody

Information sourced from Uniprot.org