| Short Description : | Rabbit polyclonal Zip12 (1-100) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLC39A12 |
| Gene ID: | 221074 |
| Uniprot ID: | S39AC_HUMAN |
| Immunogen Region: | 1-100 |
| Immunogen Sequence: | MCFRTKLSVSWVPLFLLLSR VFSTETDKPSAQDSRSRGSS GQPADLLQVLSAGDHPPHNH SRSLIKTLLEKTGCPRRRNG MQGDCNLCFEPDALLLIAGG |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SLC39A12 (NP_001138667.1). |
| Tissue Specificity | Expressed in brain and eye. |
| Function | Uniporter that promotes Zn(2+) import from the extracellular space to the cytoplasm across the cell membrane. The transport activity is temperature dependent. May play a role in neurulation and neurite extension. May play a key role in maintaining intracellular zinc content at levels that reduce the inhibitory effects of rises in oxidative stress on spermatogonia and spermatozoa viability during spermatogenesis. |
| Protein Name | Zinc Transporter Zip12Liv-1 Subfamily Of Zip Zinc Transporter 8Lzt-Hs8Solute Carrier Family 39 Member 12Zrt- And Irt-Like Protein 12Zip-12 |
| Database Links | |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinAt Low Zn(2+) Extracellular ConcentrationIs Redistributed From The Perinuclear Space To The Cytoplasm And Plasma Membrane |
| Alternative Antibody Names | Anti-Zinc Transporter Zip12 antibodyAnti-Liv-1 Subfamily Of Zip Zinc Transporter 8 antibodyAnti-Lzt-Hs8 antibodyAnti-Solute Carrier Family 39 Member 12 antibodyAnti-Zrt- And Irt-Like Protein 12 antibodyAnti-Zip-12 antibodyAnti-SLC39A12 antibodyAnti-ZIP12 antibody |
Information sourced from Uniprot.org
