| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Zip12 (1-100) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC39A12 |
| Gene ID: |
221074 |
| Uniprot ID: |
S39AC_HUMAN |
| Immunogen Region: |
1-100 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SLC39A12 (NP_001138667.1). |
| Immunogen Sequence: |
MCFRTKLSVSWVPLFLLLSR VFSTETDKPSAQDSRSRGSS GQPADLLQVLSAGDHPPHNH SRSLIKTLLEKTGCPRRRNG MQGDCNLCFEPDALLLIAGG |
| Tissue Specificity | Expressed in brain and eye. |
| Function | Uniporter that promotes Zn(2+) import from the extracellular space to the cytoplasm across the cell membrane. The transport activity is temperature dependent. May play a role in neurulation and neurite extension. May play a key role in maintaining intracellular zinc content at levels that reduce the inhibitory effects of rises in oxidative stress on spermatogonia and spermatozoa viability during spermatogenesis. |
| Protein Name | Zinc Transporter Zip12Liv-1 Subfamily Of Zip Zinc Transporter 8Lzt-Hs8Solute Carrier Family 39 Member 12Zrt- And Irt-Like Protein 12Zip-12 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinAt Low Zn(2+) Extracellular ConcentrationIs Redistributed From The Perinuclear Space To The Cytoplasm And Plasma Membrane |
| Alternative Antibody Names | Anti-Zinc Transporter Zip12 antibodyAnti-Liv-1 Subfamily Of Zip Zinc Transporter 8 antibodyAnti-Lzt-Hs8 antibodyAnti-Solute Carrier Family 39 Member 12 antibodyAnti-Zrt- And Irt-Like Protein 12 antibodyAnti-Zip-12 antibodyAnti-SLC39A12 antibodyAnti-ZIP12 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
