| Short Description : | Rabbit polyclonal anti-Zinc finger CCHC domain-containing protein 8 for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ZCCHC8 |
| Gene ID: | 55596 |
| Uniprot ID: | ZCHC8_HUMAN |
| Immunogen: | Synthesized peptide derived from part of the human protein |
| Specificity: | ZCHC8 Polyclonal Antibody detects endogenous levels of protein. |
| Function | Scaffolding subunit of the trimeric nuclear exosome targeting (NEXT) complex that is involved in the surveillance and turnover of aberrant transcripts and non-coding RNAs. NEXT functions as an RNA exosome cofactor that directs a subset of non-coding short-lived RNAs for exosomal degradation. May be involved in pre-mRNA splicing (Probable). It is required for 3'-end maturation of telomerase RNA component (TERC), TERC 3'-end targeting to the nuclear RNA exosome, and for telomerase function. |
| Protein Name | Zinc Finger Cchc Domain-Containing Protein 8Tramp-Like Complex Rna-Binding Factor Zcchc8 |
| Database Links | Reactome: R-HSA-9843970 |
| Cellular Localisation | NucleusNucleoplasmExcluded From Nucleolus |
| Alternative Antibody Names | Anti-Zinc Finger Cchc Domain-Containing Protein 8 antibodyAnti-Tramp-Like Complex Rna-Binding Factor Zcchc8 antibodyAnti-ZCCHC8 antibody |
Information sourced from Uniprot.org
