Anti-ZCCHC8 antibody (STJ191641)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Zinc finger CCHC domain-containing protein 8 for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ZCCHC8 |
| Gene ID | 55596 |
| Uniprot ID | ZCHC8_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | ZCHC8 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Scaffolding subunit of the trimeric nuclear exosome targeting (NEXT) complex that is involved in the surveillance and turnover of aberrant transcripts and non-coding RNAs. NEXT functions as an RNA exosome cofactor that directs a subset of non-coding short-lived RNAs for exosomal degradation. May be involved in pre-mRNA splicing (Probable). It is required for 3'-end maturation of telomerase RNA component (TERC), TERC 3'-end targeting to the nuclear RNA exosome, and for telomerase function. |
| Protein Name | Zinc Finger Cchc Domain-Containing Protein 8Tramp-Like Complex Rna-Binding Factor Zcchc8 |
| Database Links | Reactome: R-HSA-9843970 |
| Cellular Localisation | NucleusNucleoplasmExcluded From Nucleolus |
| Alternative Antibody Names | Anti-Zinc Finger Cchc Domain-Containing Protein 8 antibodyAnti-Tramp-Like Complex Rna-Binding Factor Zcchc8 antibodyAnti-ZCCHC8 antibody |
Information sourced from Uniprot.org