Anti-ZAP-70 antibody [L453R+L453R] (STJ16101805)

Anti-ZAP-70 antibody [L453R+L453R] (STJ16101805)

⇓ Datasheet ⇓ SDS Citations
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2bk
ImmunogenA prokaryotic recombinant protein corresponding to a portion of the N-terminus.
STJ16101805-1
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General Information

Short DescriptionMouse monoclonal anti-ZAP-70 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsIHC-P
HostMouse
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDL453R+L453R
IsotypeIgG2bk
ConjugationUnconjugated
Concentration>=449 mg/L
Dilution RangeIHC-P 1:100
FormulationPBS with sodium azide
Storage InstructionStore at 2-8°C for up to 1-year, upon receipt.

Target Information

ImmunogenA prokaryotic recombinant protein corresponding to a portion of the N-terminus.

Additional Info

Background ZAP-70 is a member of the syk family of proteins. It is expressed on T cells and NK cells and is required for the T cell receptor activation that triggers an immune response. CLL B cells that express the non-mutated immunoglobulin VH genes express levels of ZAP-70 protein that are comparable to those found in the blood T cells of healthy adults. Leukemic cells that express mutated Ig VH genes generally do not express detectable levels of ZAP-70 protein and this is correlated with the high level expression of CD38.

Information sourced from Uniprot.org

Citations

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