Anti-XDH antibody (1066-1084) (STJ115019)

Name: Anti-XDH antibody (1066-1084) (STJ115019)
SKU: STJ115019
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ115019

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Short Description	Rabbit polyclonal XDH (1066-1084) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	XDH
Gene ID	7498
Uniprot ID	XDH_HUMAN
Immunogen Region	1066-1084
Immunogen Sequence	VDKFNKENCWKKRGLCIIPT KFGISFTVPFLNQAGALLHV YTDGSVLLTHGGTEMGQGLH TKMVQVASRALKIPTSKIYI SETSTNTVPNTSPTAASVSA DLNGQAVYAACQTILKRLEP YKKKNPSGSWEDWVTAAYMD TVSLSATGFYRTPNLGYSFE TNSGNPFHYFSYGVACSEVE IDCLTGDHKNLRTDIVMDVG SSLNPAIDIGQVEGAFVQGL GLFTLEELHYSPEGSLHTR
Specificity	A synthetic peptide corresponding to a sequence within amino acids 985-1084 of human Xanthine Oxidase (XDH) (NP_000370.2).

Tissue Specificity	Detected in milk (at protein level).
Post Translational Modifications	Subject to partial proteolysis.this alters the enzyme from the dehydrogenase form (D) to the oxidase form (O). Contains sulfhydryl groups that are easily oxidized (in vitro).this alters the enzyme from the dehydrogenase form (D) to the oxidase form (O).
Function	Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species. Has also low oxidase activity towards aldehydes (in vitro).
Protein Name	Xanthine Dehydrogenase/Oxidase Includes - Xanthine Dehydrogenase Xd - Xanthine Oxidase Xo Xanthine Oxidoreductase Xor
Database Links	Reactome: R-HSA-74259 Reactome: R-HSA-8851680 Reactome: R-HSA-9748787
Cellular Localisation	Cytoplasm Peroxisome Secreted
Alternative Antibody Names	Anti-Xanthine Dehydrogenase/Oxidase Includes - Xanthine Dehydrogenase antibody Anti-Xd - Xanthine Oxidase antibody Anti-Xo antibody Anti-Xanthine Oxidoreductase antibody Anti-Xor antibody Anti-XDH antibody Anti-XDHA antibody

Information sourced from Uniprot.org