![Anti-Wilms Tumor antibody [WT49] (STJ16101804)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/152310/347157/STJ16101804_1__72304.1681999432.jpg?c=1 "Anti-Wilms Tumor antibody [WT49] (STJ16101804)")
![Anti-Wilms Tumor antibody [WT49] (STJ16101804)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/152310/347157/STJ16101804_1__72304.1681999432.jpg?c=1 "Anti-Wilms Tumor antibody [WT49] (STJ16101804)")
Anti-Wilms Tumor antibody [WT49] (STJ16101804)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenA prokaryotic recombinant protein containing 1–181 amino acids of the N-terminal of the Wilms Tumor protein.
General Information
| Short Description | Mouse monoclonal anti-Wilms Tumor for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | WT49 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | >=44 mg/L |
| Dilution Range | IHC-P 1:100 |
| Formulation | Tissue culture supernatant with sodium azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
| Immunogen | A prokaryotic recombinant protein containing 1–181 amino acids of the N-terminal of the Wilms Tumor protein. |
Additional Info
| Background | Wilms tumor protein (WT1) has a role in transcriptional regulation and is expressed in the kidney and a subset of hematopoietic cells. Alteration of transcription factor function is a common mechanism in oncogenesis. The WT1 protein contains a DNA binding domain and any deletions or point mutations of the WT1 gene which destroy this activity result in the development of the childhood nephroblastoma Wilms tumor and Denys-Drash syndrome. The description of WT1 involvement in nephroblastoma is not clear. |
Information sourced from Uniprot.org