| Host: |
Mouse |
| Applications: |
IHC-P |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-Wilms Tumor is suitable for use in Immunohistochemistry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
WT49 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG1 |
| Formulation: |
Tissue culture supernatant with sodium azide |
| Concentration: |
>=44 mg/L |
| Dilution Range: |
IHC-P 1:100 |
| Storage Instruction: |
Store at 2-8°C upon receipt. |
| Immunogen: |
A prokaryotic recombinant protein containing 1–181 amino acids of the N-terminal of the Wilms Tumor protein. |
| Background | Wilms tumor protein (WT1) has a role in transcriptional regulation and is expressed in the kidney and a subset of hematopoietic cells. Alteration of transcription factor function is a common mechanism in oncogenesis. The WT1 protein contains a DNA binding domain and any deletions or point mutations of the WT1 gene which destroy this activity result in the development of the childhood nephroblastoma Wilms tumor and Denys-Drash syndrome. The description of WT1 involvement in nephroblastoma is not clear. |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
