| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-VTI1A (1-180) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
VTI1A |
| Gene ID: |
143187 |
| Uniprot ID: |
VTI1A_HUMAN |
| Immunogen Region: |
1-180 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human VTI1A (NP_660207.2). |
| Immunogen Sequence: |
MSSDFEGYEQDFAVLTAEIT SKIARVPRLPPDEKKQMVAN VEKQLEEAKELLEQMDLEVR EIPPQSRGMYSNRMRSYKQE MGKLETDFKRSRIAYSDEVR NELLGDDGNSSENQRAHLLD NTERLERSSRRLEAGYQIAV ETEQIGQEMLENLSHDREKI QRARERLRETDANLGKSSRI |
| Function | V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non-conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2. May be involved in increased cytokine secretion associated with cellular senescence. |
| Protein Name | Vesicle Transport Through Interaction With T-Snares Homolog 1aVesicle Transport V-Snare Protein Vti1-Like 2Vti1-Rp2 |
| Database Links | Reactome: R-HSA-6811438Reactome: R-HSA-6811440 |
| Cellular Localisation | Cytoplasmic VesicleGolgi Apparatus MembraneSingle-Pass Type Iv Membrane Protein |
| Alternative Antibody Names | Anti-Vesicle Transport Through Interaction With T-Snares Homolog 1a antibodyAnti-Vesicle Transport V-Snare Protein Vti1-Like 2 antibodyAnti-Vti1-Rp2 antibodyAnti-VTI1A antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
