Anti-VTI1A antibody (1-180) (STJ27141)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal VTI1A (1-180) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | VTI1A |
| Gene ID | 143187 |
| Uniprot ID | VTI1A_HUMAN |
| Immunogen Region | 1-180 |
| Immunogen Sequence | MSSDFEGYEQDFAVLTAEIT SKIARVPRLPPDEKKQMVAN VEKQLEEAKELLEQMDLEVR EIPPQSRGMYSNRMRSYKQE MGKLETDFKRSRIAYSDEVR NELLGDDGNSSENQRAHLLD NTERLERSSRRLEAGYQIAV ETEQIGQEMLENLSHDREKI QRARERLRETDANLGKSSRI |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human VTI1A (NP_660207.2). |
Additional Info
| Function | V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non-conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2. May be involved in increased cytokine secretion associated with cellular senescence. |
| Protein Name | Vesicle Transport Through Interaction With T-Snares Homolog 1aVesicle Transport V-Snare Protein Vti1-Like 2Vti1-Rp2 |
| Database Links | Reactome: R-HSA-6811438Reactome: R-HSA-6811440 |
| Cellular Localisation | Cytoplasmic VesicleGolgi Apparatus MembraneSingle-Pass Type Iv Membrane Protein |
| Alternative Antibody Names | Anti-Vesicle Transport Through Interaction With T-Snares Homolog 1a antibodyAnti-Vesicle Transport V-Snare Protein Vti1-Like 2 antibodyAnti-Vti1-Rp2 antibodyAnti-VTI1A antibody |
Information sourced from Uniprot.org