• Western blot analysis of lysates from THP-1 cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-VPS50 antibody (177-227 aa) (STJ193730)

SKU:
STJ193730

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Syndetin (177-227 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: VPS50
Gene ID: 55610
Uniprot ID: VPS50_HUMAN
Immunogen Region: 177-227 aa
Specificity: This antibody detects endogenous levels of CC132 at Human/Mouse
Immunogen: Synthesized peptide derived from the human CC132 at the amino acid range 177-227
Function Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane. Within the EARP complex, required to tether the complex to recycling endosomes. Not involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).
Protein Name Syndetin
Coiled-Coil Domain-Containing Protein 132
Earp/Garpii Complex Subunit Vps50
Cellular Localisation Recycling Endosome
Membrane
Associates With Membranes In An Eipr1-Dependent Manner
Alternative Antibody Names Anti-Syndetin antibody
Anti-Coiled-Coil Domain-Containing Protein 132 antibody
Anti-Earp/Garpii Complex Subunit Vps50 antibody
Anti-VPS50 antibody
Anti-CCDC132 antibody
Anti-KIAA1861 antibody

Information sourced from Uniprot.org

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