Anti-VPS50 antibody (177-227 aa) (STJ193730)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human CC132 at the amino acid range 177-227
General Information
| Short Description | Rabbit polyclonal anti-Syndetin (177-227 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | VPS50 |
| Gene ID | 55610 |
| Uniprot ID | VPS50_HUMAN |
| Immunogen | Synthesized peptide derived from the human CC132 at the amino acid range 177-227 |
| Immunogen Region | 177-227 aa |
| Specificity | This antibody detects endogenous levels of CC132 at Human/Mouse |
Additional Info
| Function | Acts as a component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane. Within the EARP complex, required to tether the complex to recycling endosomes. Not involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). |
| Protein Name | SyndetinCoiled-Coil Domain-Containing Protein 132Earp/Garpii Complex Subunit Vps50 |
| Database Links | |
| Cellular Localisation | Recycling EndosomeMembraneAssociates With Membranes In An Eipr1-Dependent Manner |
| Alternative Antibody Names | Anti-Syndetin antibodyAnti-Coiled-Coil Domain-Containing Protein 132 antibodyAnti-Earp/Garpii Complex Subunit Vps50 antibodyAnti-VPS50 antibodyAnti-CCDC132 antibodyAnti-KIAA1861 antibody |
Information sourced from Uniprot.org