• Western blot analysis of extracts of various cell lines, using VPS37A antibody (STJ116094) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-VPS37A antibody (224-397) (STJ116094)

SKU:
STJ116094

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Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-VPS37A (224-397) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: VPS37A
Gene ID: 137492
Uniprot ID: VP37A_HUMAN
Immunogen Region: 224-397
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 224-397 of human VPS37A (NP_689628.2).
Immunogen Sequence: MPDVPDAFPELSELSVSQLT DMNEQEEVLLEQFLTLPQLK QIITDKDDLVKSIEELARKN LLLEPSLEAKRQTVLDKYEL LTQMKSTFEKKMQRQHELSE SCSASALQARLKVAAHEAEE ESDNIAEDFLEGKMEIDDFL SSFMEKRTICHCRRAKEEKL QQAIAMHSQFHAPL
Tissue Specificity Widely expressed. Examined tissues include heart, brain, placenta, liver, skeletal muscle, kidney and pancreas. More abundant in liver. Strongly decreased or undetected in hepatomas.
Function Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
Protein Name Vacuolar Protein Sorting-Associated Protein 37a
Hvps37a
Escrt-I Complex Subunit Vps37a
Hepatocellular Carcinoma-Related Protein 1
Database Links Reactome: R-HSA-162588
Reactome: R-HSA-174490
Reactome: R-HSA-917729
Reactome: R-HSA-9610379
Reactome: R-HSA-9615710
Cellular Localisation Late Endosome Membrane
Peripheral Membrane Protein
Nucleus
Alternative Antibody Names Anti-Vacuolar Protein Sorting-Associated Protein 37a antibody
Anti-Hvps37a antibody
Anti-Escrt-I Complex Subunit Vps37a antibody
Anti-Hepatocellular Carcinoma-Related Protein 1 antibody
Anti-VPS37A antibody
Anti-HCRP1 antibody

Information sourced from Uniprot.org

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