• Western blot analysis of extracts of various cell lines, using USP24 antibody (STJ112599) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Anti-USP24 antibody (2431-2620) (STJ112599)

SKU:
STJ112599

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-USP24 (2431-2620) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:1000-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: USP24
Gene ID: 23358
Uniprot ID: UBP24_HUMAN
Immunogen Region: 2431-2620
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 2431-2620 of human USP24 (NP_056121.2).
Immunogen Sequence: FTMLHFIKNQLETAPPHELK NTFQLLHEILVIEDPIQVER VKFVFETENGLLALMHHSNH VDSSRCYQCVKFLVTLAQKC PAAKEYFKENSHHWSWAVQW LQKKMSEHYWTPQSNVSNET STGKTFQRTISAQDTLAYAT ALLNEKEQSGSSNGSESSPA NENGDRHLQQGSESPMMIGE LRSDLDDVDP
Function Ubiquitin-specific protease that regulates cell survival in various contexts through modulating the protein stability of some of its substrates including DDB2, MCL1 or TP53. Plays a positive role on ferritinophagy where ferritin is degraded in lysosomes and releases free iron.
Protein Name Ubiquitin Carboxyl-Terminal Hydrolase 24
Deubiquitinating Enzyme 24
Ubiquitin Thioesterase 24
Ubiquitin-Specific-Processing Protease 24
Database Links Reactome: R-HSA-5689880
Alternative Antibody Names Anti-Ubiquitin Carboxyl-Terminal Hydrolase 24 antibody
Anti-Deubiquitinating Enzyme 24 antibody
Anti-Ubiquitin Thioesterase 24 antibody
Anti-Ubiquitin-Specific-Processing Protease 24 antibody
Anti-USP24 antibody
Anti-KIAA1057 antibody

Information sourced from Uniprot.org

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