Anti-UROD antibody (1-367) (STJ27446)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal UROD (1-367) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | UROD |
| Gene ID | 7389 |
| Uniprot ID | DCUP_HUMAN |
| Immunogen Region | 1-367 |
| Immunogen Sequence | MEANGLGPQGFPELKNDTFL RAAWGEETDYTPVWCMRQAG RYLPEFRETRAAQDFFSTCR SPEACCELTLQPLRRFPLDA AIIFSDILVVPQALGMEVTM VPGKGPSFPEPLREEQDLER LRDPEVVASELGYVFQAITL TRQRLAGRVPLIGFAGAPWT LMTYMVEGGGSSTMAQAKRW LYQRPQASHQLLRILTDALV PYLVGQVVAGAQALQLFESH AGHLGPQLFNKFALPYIRD |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-367 of human UROD (NP_000365.3). |
Additional Info
| Function | Catalyzes the sequential decarboxylation of the four acetate side chains of uroporphyrinogen to form coproporphyrinogen and participates in the fifth step in the heme biosynthetic pathway. Isomer I or isomer III of uroporphyrinogen may serve as substrate, but only coproporphyrinogen III can ultimately be converted to heme. In vitro also decarboxylates pentacarboxylate porphyrinogen I. |
| Protein Name | Uroporphyrinogen DecarboxylaseUpdUro-D |
| Database Links | Reactome: R-HSA-189451 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Uroporphyrinogen Decarboxylase antibodyAnti-Upd antibodyAnti-Uro-D antibodyAnti-UROD antibody |
Information sourced from Uniprot.org