| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-UROD (1-367) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
UROD |
| Gene ID: |
7389 |
| Uniprot ID: |
DCUP_HUMAN |
| Immunogen Region: |
1-367 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-367 of human UROD (NP_000365.3). |
| Immunogen Sequence: |
MEANGLGPQGFPELKNDTFL RAAWGEETDYTPVWCMRQAG RYLPEFRETRAAQDFFSTCR SPEACCELTLQPLRRFPLDA AIIFSDILVVPQALGMEVTM VPGKGPSFPEPLREEQDLER LRDPEVVASELGYVFQAITL TRQRLAGRVPLIGFAGAPWT LMTYMVEGGGSSTMAQAKRW LYQRPQASHQLLRILTDALV PYLVGQVVAGAQALQLFESH AGHLGPQLFNKFALPYIRD |
| Function | Catalyzes the sequential decarboxylation of the four acetate side chains of uroporphyrinogen to form coproporphyrinogen and participates in the fifth step in the heme biosynthetic pathway. Isomer I or isomer III of uroporphyrinogen may serve as substrate, but only coproporphyrinogen III can ultimately be converted to heme. In vitro also decarboxylates pentacarboxylate porphyrinogen I. |
| Protein Name | Uroporphyrinogen DecarboxylaseUpdUro-D |
| Database Links | Reactome: R-HSA-189451 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Uroporphyrinogen Decarboxylase antibodyAnti-Upd antibodyAnti-Uro-D antibodyAnti-UROD antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
