• Western blot analysis of various lysates using UPB1 Rabbit polyclonal antibody (STJ117647) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-UPB1 antibody (1-240) (STJ117647)

SKU:
STJ117647

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Host: Rabbit
Applications: WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-UPB1 (1-240) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:200-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: UPB1
Gene ID: 51733
Uniprot ID: BUP1_HUMAN
Immunogen Region: 1-240
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human UPB1 (NP_057411.1).
Immunogen Sequence: MAGAEWKSLEECLEKHLPLP DLQEVKRVLYGKELRKLDLP REAFEAASREDFELQGYAFE AAEEQLRRPRIVHVGLVQNR IPLPANAPVAEQVSALHRRI KAIVEVAAMCGVNIICFQEA WTMPFAFCTREKLPWTEFAE SAEDGPTTRFCQKLAKNHDM VVVSPILERDSEHGDVLWNT AVVISNSGAVLGKTRKNHIP RVGDFNESTYYMEGNLGHPV FQTQFGRIAVNICYGRHHP
Tissue Specificity Detected in liver (at protein level).
Function Catalyzes a late step in pyrimidine degradation. Converts N-carbamoyl-beta-alanine (3-ureidopropanoate) into beta-alanine, ammonia and carbon dioxide. Likewise, converts N-carbamoyl-beta-aminoisobutyrate (3-ureidoisobutyrate) into beta-aminoisobutyrate, ammonia and carbon dioxide (Probable).
Protein Name Beta-Ureidopropionase
Bup-1
Beta-Alanine Synthase
N-Carbamoyl-Beta-Alanine Amidohydrolase
Database Links Reactome: R-HSA-73621
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Beta-Ureidopropionase antibody
Anti-Bup-1 antibody
Anti-Beta-Alanine Synthase antibody
Anti-N-Carbamoyl-Beta-Alanine Amidohydrolase antibody
Anti-UPB1 antibody
Anti-BUP1 antibody

Information sourced from Uniprot.org

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