| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | UPB1 |
| Gene ID: | 51733 |
| Uniprot ID: | BUP1_HUMAN |
| Immunogen Region: | 1-240 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human UPB1 (NP_057411.1). |
| Immunogen Sequence: | MAGAEWKSLEECLEKHLPLP DLQEVKRVLYGKELRKLDLP REAFEAASREDFELQGYAFE AAEEQLRRPRIVHVGLVQNR IPLPANAPVAEQVSALHRRI KAIVEVAAMCGVNIICFQEA WTMPFAFCTREKLPWTEFAE SAEDGPTTRFCQKLAKNHDM VVVSPILERDSEHGDVLWNT AVVISNSGAVLGKTRKNHIP RVGDFNESTYYMEGNLGHPV FQTQFGRIAVNICYGRHHP |
| Tissue Specificity | Detected in liver (at protein level). |
| Function | Catalyzes a late step in pyrimidine degradation. Converts N-carbamoyl-beta-alanine (3-ureidopropanoate) into beta-alanine, ammonia and carbon dioxide. Likewise, converts N-carbamoyl-beta-aminoisobutyrate (3-ureidoisobutyrate) into beta-aminoisobutyrate, ammonia and carbon dioxide (Probable). |
| Protein Name | Beta-UreidopropionaseBup-1Beta-Alanine SynthaseN-Carbamoyl-Beta-Alanine Amidohydrolase |
| Database Links | Reactome: R-HSA-73621 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Beta-Ureidopropionase antibodyAnti-Bup-1 antibodyAnti-Beta-Alanine Synthase antibodyAnti-N-Carbamoyl-Beta-Alanine Amidohydrolase antibodyAnti-UPB1 antibodyAnti-BUP1 antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and TRK fused gene (TRK fused gene (TFG) ) knockout (KO) HeLa cells, using [KO Validated] TRK fused gene (TFG) Rabbit polyclonal antibody (STJ11100734) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89672/358167/STJ11100734_1__93210.1713122472.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and TRK fused gene (TRK fused gene (TFG) ) knockout (KO) HeLa cells, using [KO Validated] TRK fused gene (TFG) Rabbit polyclonal antibody (STJ11100734) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
