| Short Description : | Rabbit polyclonal Udp-Glucuronosyltransferase 2b17 (50-200) antibody for use in IF, ICC and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | UGT2B17 |
| Gene ID: | 7367 |
| Uniprot ID: | UDB17_HUMAN |
| Immunogen Region: | 50-200 |
| Immunogen Sequence: | GHEVIVLTSSASILVNASKS SAIKLEVYPTSLTKNDLEDF FMKMFDRWTYSISKNTFWSY FSQLQELCWEYSDYNIKLCE DAVLNKKLMRKLQESKFDVL LADAVNPCGELLAELLNIPF LYSLRFSVGYTVEKNGGGFL FPPSYVPVVMS |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-200 of human UGT2B17 (NP_001068.1). |
| Tissue Specificity | Expressed in various tissues including the liver, kidney, testis, uterus, placenta, mammary gland, adrenal gland, skin and prostate. |
| Function | UDP-glucuronosyltransferase (UGT) that catalyzes phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase the metabolite's water solubility, thereby facilitating excretion into either the urine or bile. Catalyzes the glucuronidation of endogenous steroid hormones such as androgens (epitestosterone, androsterone) and estrogens (estradiol, epiestradiol). |
| Protein Name | Udp-Glucuronosyltransferase 2b17Udpgt 2b17Ugt2b17C19-Steroid-Specific Udp-GlucuronosyltransferaseC19-Steroid-Specific Udpgt |
| Database Links | Reactome: R-HSA-156588Reactome: R-HSA-9749641Reactome: R-HSA-9757110 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Udp-Glucuronosyltransferase 2b17 antibodyAnti-Udpgt 2b17 antibodyAnti-Ugt2b17 antibodyAnti-C19-Steroid-Specific Udp-Glucuronosyltransferase antibodyAnti-C19-Steroid-Specific Udpgt antibodyAnti-UGT2B17 antibody |
Information sourced from Uniprot.org
