| Host: |
Rabbit |
| Applications: |
IF |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Udp-Glucuronosyltransferase 2b17 (50-200) is suitable for use in Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
UGT2B17 |
| Gene ID: |
7367 |
| Uniprot ID: |
UDB17_HUMAN |
| Immunogen Region: |
50-200 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 50-200 of human UGT2B17 (NP_001068.1). |
| Immunogen Sequence: |
GHEVIVLTSSASILVNASKS SAIKLEVYPTSLTKNDLEDF FMKMFDRWTYSISKNTFWSY FSQLQELCWEYSDYNIKLCE DAVLNKKLMRKLQESKFDVL LADAVNPCGELLAELLNIPF LYSLRFSVGYTVEKNGGGFL FPPSYVPVVMS |
| Tissue Specificity | Expressed in various tissues including the liver, kidney, testis, uterus, placenta, mammary gland, adrenal gland, skin and prostate. |
| Function | UDP-glucuronosyltransferase (UGT) that catalyzes phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase the metabolite's water solubility, thereby facilitating excretion into either the urine or bile. Catalyzes the glucuronidation of endogenous steroid hormones such as androgens (epitestosterone, androsterone) and estrogens (estradiol, epiestradiol). |
| Protein Name | Udp-Glucuronosyltransferase 2b17Udpgt 2b17Ugt2b17C19-Steroid-Specific Udp-GlucuronosyltransferaseC19-Steroid-Specific Udpgt |
| Database Links | Reactome: R-HSA-156588Reactome: R-HSA-9749641Reactome: R-HSA-9757110 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Udp-Glucuronosyltransferase 2b17 antibodyAnti-Udpgt 2b17 antibodyAnti-Ugt2b17 antibodyAnti-C19-Steroid-Specific Udp-Glucuronosyltransferase antibodyAnti-C19-Steroid-Specific Udpgt antibodyAnti-UGT2B17 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
