| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-UGT1A6 (65-270) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
UGT1A6 |
| Gene ID: |
54578 |
| Uniprot ID: |
UD16_HUMAN |
| Immunogen Region: |
65-270 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 65-270 of human UGT1A6 (NP_001063.2). |
| Immunogen Sequence: |
LLLKESKYYTRKIYPVPYDQ EELKNRYQSFGNNHFAERSF LTAPQTEYRNNMIVIGLYFI NCQSLLQDRDTLNFFKESKF DALFTDPALPCGVILAEYLG LPSVYLFRGFPCSLEHTFSR SPDPVSYIPRCYTKFSDHMT FSQRVANFLVNLLEPYLFYC LFSKYEELASAVLKRDVDII TLYQKVSVWLLRYDFVLEYP RPVMPN |
| Tissue Specificity | Expressed in skin. Isoforms 1 and 3 are expressed in kidney and liver. Isoform 1 but not isoform 2 is expressed in colon, esophagus and small intestine. |
| Function | UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols. Isoform 3 lacks transferase activity but acts as a negative regulator of isoform 1. |
| Protein Name | Udp-Glucuronosyltransferase 1-6Udpgt 1-6Ugt1*6Ugt1-06Ugt1.6Phenol-Metabolizing Udp-GlucuronosyltransferaseUdp-Glucuronosyltransferase 1-FUgt-1fUgt1fUdp-Glucuronosyltransferase 1a6 |
| Database Links | Reactome: R-HSA-156588Reactome: R-HSA-9749641Reactome: R-HSA-9753281 |
| Cellular Localisation | MicrosomeEndoplasmic Reticulum MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Udp-Glucuronosyltransferase 1-6 antibodyAnti-Udpgt 1-6 antibodyAnti-Ugt1*6 antibodyAnti-Ugt1-06 antibodyAnti-Ugt1.6 antibodyAnti-Phenol-Metabolizing Udp-Glucuronosyltransferase antibodyAnti-Udp-Glucuronosyltransferase 1-F antibodyAnti-Ugt-1f antibodyAnti-Ugt1f antibodyAnti-Udp-Glucuronosyltransferase 1a6 antibodyAnti-UGT1A6 antibodyAnti-GNT1 antibodyAnti-UGT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
