Anti-U2AF1 antibody (1-100) (STJ115132)

Name: Anti-U2AF1 antibody (1-100) (STJ115132)
SKU: STJ115132
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ115132

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Short Description	Rabbit polyclonal U2AF1 (1-100) antibody for use in WB, IHC-P, IP and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P/IP/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 IHC-P:1:100-1:200 IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cells ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements
Formulation	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	U2AF1
Gene ID	7307
Uniprot ID	U2AF1_HUMAN
Immunogen Region	1-100
Immunogen Sequence	MAEYLASIFGTEKDKVNCSF YFKIGACRHGDRCSRLHNKP TFSQTIALLNIYRNPQNSSQ SADGLRCAVSDVEMQEHYDE FFEEVFTEMEEKYGEVEEMN
Specificity	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human U2AF1 (NP_006749.1).

Function	Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron.
Protein Name	Splicing Factor U2af 35 Kda Subunit U2 Auxiliary Factor 35 Kda Subunit U2 Small Nuclear Rna Auxiliary Factor 1 U2 Snrnp Auxiliary Factor Small Subunit
Database Links	Reactome: R-HSA-159236 Reactome: R-HSA-72163 Reactome: R-HSA-72187 Reactome: R-HSA-73856
Cellular Localisation	Nucleus Nucleus Speckle
Alternative Antibody Names	Anti-Splicing Factor U2af 35 Kda Subunit antibody Anti-U2 Auxiliary Factor 35 Kda Subunit antibody Anti-U2 Small Nuclear Rna Auxiliary Factor 1 antibody Anti-U2 Snrnp Auxiliary Factor Small Subunit antibody Anti-U2AF1 antibody Anti-U2AF35 antibody Anti-U2AFBP antibody Anti-FP793 antibody

Information sourced from Uniprot.org