Anti-TXN2 antibody (1-166) (STJ28865)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TXN2 (1-166) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TXN2 |
| Gene ID | 25828 |
| Uniprot ID | THIOM_HUMAN |
| Immunogen Region | 1-166 |
| Immunogen Sequence | MAQRLLLRRFLASVISRKPS QGQWPPLTSRALQTPQCSPG GLTVTPNPARTIYTTRISLT TFNIQDGPDFQDRVVNSETP VVVDFHAQWCGPCKILGPRL EKMVAKQHGKVVMAKVDIDD HTDLAIEYEVSAVPTVLAMK NGDVVDKFVGIKDEDQLEAF LKKLIG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-166 of human Thioredoxin 2 (Trx2/Thioredoxin 2 (Trx2/TXN2) ) (NP_036605.2). |
Additional Info
| Tissue Specificity | Widely expressed in adult (at protein level) and fetal tissues. |
| Function | Important for the control of mitochondrial reactive oxygen species homeostasis, apoptosis regulation and cell viability Is involved in various redox reactions including the reduction of protein disulfide bonds, through the reversible oxidation of its active center dithiol to a disulfide. |
| Protein Name | Thioredoxin - MitochondrialMtrxMt-TrxThioredoxin-2 |
| Database Links | Reactome: R-HSA-1614558Reactome: R-HSA-3299685 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Thioredoxin - Mitochondrial antibodyAnti-Mtrx antibodyAnti-Mt-Trx antibodyAnti-Thioredoxin-2 antibodyAnti-TXN2 antibodyAnti-TRX2 antibody |
Information sourced from Uniprot.org