• Western blot analysis of lysates from COLO205 and HeLa cells, using TUSC3 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of HeLa cells using N33 Polyclonal Antibody
  • Immunofluorescence analysis of HeLa cells using TUSC3 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using N33 Polyclonal Antibody

Anti-TUSC3 antibody (131-180) (STJ94326)

SKU:
STJ94326

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Tumor suppressor candidate 3 (131-180) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TUSC3
Gene ID: 7991
Uniprot ID: TUSC3_HUMAN
Immunogen Region: 131-180
Specificity: N33 Polyclonal Antibody detects endogenous levels of N33 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from human TUSC3. AA range:131-180
Tissue Specificity Expressed in most non-lymphoid cells and tissues examined, including prostate, lung, liver, colon, heart, kidney and pancreas.
Function Acts as accessory component of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Involved in N-glycosylation of STT3B-dependent substrates. Specifically required for the glycosylation of a subset of acceptor sites that are near cysteine residues.in this function seems to act redundantly with MAGT1. In its oxidized form proposed to form transient mixed disulfides with a glycoprotein substrate to facilitate access of STT3B to the unmodified acceptor site. Has also oxidoreductase-independent functions in the STT3B-containing OST complex possibly involving substrate recognition. Magnesium transporter.
Protein Name Tumor Suppressor Candidate 3
Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit Tusc3
Oligosaccharyl Transferase Subunit Tusc3
Magnesium Uptake/Transporter Tusc3
Protein N33
Database Links Reactome: R-HSA-446203
Reactome: R-HSA-5223345
Reactome: R-HSA-9694548
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Tumor Suppressor Candidate 3 antibody
Anti-Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit Tusc3 antibody
Anti-Oligosaccharyl Transferase Subunit Tusc3 antibody
Anti-Magnesium Uptake/Transporter Tusc3 antibody
Anti-Protein N33 antibody
Anti-TUSC3 antibody
Anti-N33 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance