| Short Description : | Mouse monoclonal anti-Tubulin gamma-1 chain for use in WB, IHC and IF in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IF |
| Host: | Mouse |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | 6C12 |
| Isotype: | IgG1 |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range: | WB 1:1000-2000IHC 1:100-200IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TUBG1 |
| Gene ID: | 7283 |
| Uniprot ID: | TBG1_HUMAN |
| Immunogen: | Synthetic Peptide of Gamma Tubulin |
| Specificity: | Gamma Tubulin protein detects endogenous levels of TUBG1 |
| Function | Tubulin is the major constituent of microtubules, protein filaments consisting of alpha- and beta-tubulin heterodimers. Gamma-tubulin is a key component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation. The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation. |
| Protein Name | Tubulin Gamma-1 ChainGamma-1-TubulinGamma-Tubulin Complex Component 1Gcp-1 |
| Database Links | Reactome: R-HSA-2565942Reactome: R-HSA-380259Reactome: R-HSA-380270Reactome: R-HSA-380284Reactome: R-HSA-380320Reactome: R-HSA-5620912Reactome: R-HSA-8854518 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeSpindleLocalizes To Mitotic Spindle Microtubules |
| Alternative Antibody Names | Anti-Tubulin Gamma-1 Chain antibodyAnti-Gamma-1-Tubulin antibodyAnti-Gamma-Tubulin Complex Component 1 antibodyAnti-Gcp-1 antibodyAnti-TUBG1 antibodyAnti-TUBG antibody |
Information sourced from Uniprot.org
