Anti-TUBG1 antibody [6C12] (STJ97759)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenSynthetic Peptide of Gamma Tubulin
General Information
| Short Description | Mouse monoclonal anti-Tubulin gamma-1 chain for use in WB, IHC and IF in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF |
| Host | Mouse |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 6C12 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range | WB 1:1000-2000IHC 1:100-200IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TUBG1 |
| Gene ID | 7283 |
| Uniprot ID | TBG1_HUMAN |
| Immunogen | Synthetic Peptide of Gamma Tubulin |
| Specificity | Gamma Tubulin protein detects endogenous levels of TUBG1 |
Additional Info
| Function | Tubulin is the major constituent of microtubules, protein filaments consisting of alpha- and beta-tubulin heterodimers. Gamma-tubulin is a key component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation. The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation. |
| Protein Name | Tubulin Gamma-1 ChainGamma-1-TubulinGamma-Tubulin Complex Component 1Gcp-1 |
| Database Links | Reactome: R-HSA-2565942Reactome: R-HSA-380259Reactome: R-HSA-380270Reactome: R-HSA-380284Reactome: R-HSA-380320Reactome: R-HSA-5620912Reactome: R-HSA-8854518 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeSpindleLocalizes To Mitotic Spindle Microtubules |
| Alternative Antibody Names | Anti-Tubulin Gamma-1 Chain antibodyAnti-Gamma-1-Tubulin antibodyAnti-Gamma-Tubulin Complex Component 1 antibodyAnti-Gcp-1 antibodyAnti-TUBG1 antibodyAnti-TUBG antibody |
Information sourced from Uniprot.org