Anti-TSSK4 antibody (211-260 aa) (STJ96132)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human TSSK4 at the amino acid range 211-260
General Information
| Short Description | Rabbit polyclonal anti-Testis-specific serine/threonine-protein kinase 4 (211-260 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TSSK4 |
| Gene ID | 283629 |
| Uniprot ID | TSSK4_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human TSSK4 at the amino acid range 211-260 |
| Immunogen Region | 211-260 aa |
| Specificity | TSSK 4 Polyclonal Antibody detects endogenous levels of TSSK 4 protein. |
Additional Info
| Post Translational Modifications | Activated by autophosphorylation on Thr-197. ODF2 potentiates the autophosphorylation activity of TSSK4 at Thr-197. Ubiquitinated.HSP90 activity negatively regulates ubiquitination and degradation. |
| Function | Serine/threonine kinase which is involved in male germ cell development and in mature sperm function. May be involved in the Cre/Creb signaling pathway. Phosphorylates CREB1 on 'Ser-133' in vitro and can stimulate Cre/Creb pathway in cells. Phosphorylates CREM on 'Ser-116' in vitro. Phosphorylates ODF2 on 'Ser-95'. |
| Protein Name | Testis-Specific Serine/Threonine-Protein Kinase 4Tsk-4Tssk-4Testis-Specific Kinase 4Serine/Threonine-Protein Kinase 22e |
| Database Links | |
| Cellular Localisation | Cytoplasmic VesicleSecretory VesicleAcrosomeCell ProjectionCiliumFlagellumIn SpermatozoaPresent In The Sperm Head And In The Flagellum |
| Alternative Antibody Names | Anti-Testis-Specific Serine/Threonine-Protein Kinase 4 antibodyAnti-Tsk-4 antibodyAnti-Tssk-4 antibodyAnti-Testis-Specific Kinase 4 antibodyAnti-Serine/Threonine-Protein Kinase 22e antibodyAnti-TSSK4 antibodyAnti-C14orf20 antibodyAnti-STK22E antibodyAnti-TSSK5 antibody |
Information sourced from Uniprot.org