Host: |
Rabbit |
Applications: |
WB/ELISA |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Testis-specific serine/threonine-protein kinase 4 (211-260 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000ELISA 1:10000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
TSSK4 |
Gene ID: |
283629 |
Uniprot ID: |
TSSK4_HUMAN |
Immunogen Region: |
211-260 aa |
Specificity: |
TSSK 4 Polyclonal Antibody detects endogenous levels of TSSK 4 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human TSSK4 at the amino acid range 211-260 |
Post Translational Modifications | Activated by autophosphorylation on Thr-197. ODF2 potentiates the autophosphorylation activity of TSSK4 at Thr-197. Ubiquitinated.HSP90 activity negatively regulates ubiquitination and degradation. |
Function | Serine/threonine kinase which is involved in male germ cell development and in mature sperm function. May be involved in the Cre/Creb signaling pathway. Phosphorylates CREB1 on 'Ser-133' in vitro and can stimulate Cre/Creb pathway in cells. Phosphorylates CREM on 'Ser-116' in vitro. Phosphorylates ODF2 on 'Ser-95'. |
Protein Name | Testis-Specific Serine/Threonine-Protein Kinase 4Tsk-4Tssk-4Testis-Specific Kinase 4Serine/Threonine-Protein Kinase 22e |
Cellular Localisation | Cytoplasmic VesicleSecretory VesicleAcrosomeCell ProjectionCiliumFlagellumIn SpermatozoaPresent In The Sperm Head And In The Flagellum |
Alternative Antibody Names | Anti-Testis-Specific Serine/Threonine-Protein Kinase 4 antibodyAnti-Tsk-4 antibodyAnti-Tssk-4 antibodyAnti-Testis-Specific Kinase 4 antibodyAnti-Serine/Threonine-Protein Kinase 22e antibodyAnti-TSSK4 antibodyAnti-C14orf20 antibodyAnti-STK22E antibodyAnti-TSSK5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance