Anti-TSN antibody (50-150) (STJ11100537)

Name: Anti-TSN antibody (50-150) (STJ11100537)
SKU: STJ11100537
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ11100537

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Short Description	Rabbit polyclonal TSN (50-150) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P/IF/ICC/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 IHC-P:1:50-1:200 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	TSN
Gene ID	7247
Uniprot ID	TSN_HUMAN
Immunogen Region	50-150
Immunogen Sequence	GFQDIPKRCLKAREHFGTVK THLTSLKTKFPAEQYYRFHE HWRFVLQRLVFLAAFVVYLE TETLVTREAVTEILGIEPDR EKGFHLDVEDYLSGVLILAS E
Specificity	A synthetic peptide corresponding to a sequence within amino acids 50-150 of human TSN (NP_004613.1).

Function	DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots. Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.
Protein Name	Translin Component 3 Of Promoter Of Risc C3po
Database Links	Reactome: R-HSA-426486
Cellular Localisation	Cytoplasm Nucleus
Alternative Antibody Names	Anti-Translin antibody Anti-Component 3 Of Promoter Of Risc antibody Anti-C3po antibody Anti-TSN antibody

Information sourced from Uniprot.org