Host: |
Rabbit |
Applications: |
WB/IHC/IF |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-TSN (50-150) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000IHC-P 1:50-1:200IF/ICC 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
TSN |
Gene ID: |
7247 |
Uniprot ID: |
TSN_HUMAN |
Immunogen Region: |
50-150 |
Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human TSN (NP_004613.1). |
Immunogen Sequence: |
GFQDIPKRCLKAREHFGTVK THLTSLKTKFPAEQYYRFHE HWRFVLQRLVFLAAFVVYLE TETLVTREAVTEILGIEPDR EKGFHLDVEDYLSGVLILAS E |
Function | DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots. Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand. |
Protein Name | TranslinComponent 3 Of Promoter Of RiscC3po |
Database Links | Reactome: R-HSA-426486 |
Cellular Localisation | CytoplasmNucleus |
Alternative Antibody Names | Anti-Translin antibodyAnti-Component 3 Of Promoter Of Risc antibodyAnti-C3po antibodyAnti-TSN antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance