• STJ71557 (1µg/ml) staining of Human Pancreas lysate (35µg protein in RIPA buffer). Detected by chemiluminescence.

Anti-TRPV5 antibody (Internal) (STJ71557)

SKU:
STJ71557-100

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Host: Goat
Applications: Pep-ELISA/WB/ICC/IF
Reactivity: Human/Mouse/Rat/Dog/Pig/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-TRPV5 (Internal) is suitable for use in ELISA, Western Blot, Immunocytochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-1-3µg/ml
ELISA-antibody detection limit dilution 1:16000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: TRPV5
Gene ID: 56302
Uniprot ID: TRPV5_HUMAN
Immunogen Region: Internal
Accession Number: NP_062815.2
Immunogen Sequence: SHRGWEILRQNT
Post Translational Modifications Glycosylated.
Function Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine. Required for normal Ca(2+) reabsorption in the kidney distal convoluted tubules. The channel is activated by low internal calcium level and the current exhibits an inward rectification. A Ca(2+)-dependent feedback regulation includes fast channel inactivation and slow current decay. Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.
Protein Name Transient Receptor Potential Cation Channel Subfamily V Member 5
Trpv5
Calcium Transport Protein 2
Cat2
Epithelial Calcium Channel 1
Ecac
Ecac1
Osm-9-Like Trp Channel 3
Otrpc3
Database Links Reactome: R-HSA-3295583
Cellular Localisation Apical Cell Membrane
Multi-Pass Membrane Protein
Colocalized With S100a10 And Anax2 Along The Apical Domain Of Kidney Distal Tubular Cells
The Expression Of The Glycosylated Form In The Cell Membrane Is Increased In The Presence Of Wnk3
Alternative Antibody Names Anti-Transient Receptor Potential Cation Channel Subfamily V Member 5 antibody
Anti-Trpv5 antibody
Anti-Calcium Transport Protein 2 antibody
Anti-Cat2 antibody
Anti-Epithelial Calcium Channel 1 antibody
Anti-Ecac antibody
Anti-Ecac1 antibody
Anti-Osm-9-Like Trp Channel 3 antibody
Anti-Otrpc3 antibody
Anti-TRPV5 antibody
Anti-ECAC1 antibody

Information sourced from Uniprot.org