Anti-TRPC7 antibody (Internal) (STJ71876)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-TRPC7 (Internal) is suitable for use in ELISA, Western Blot and Immunoprecipitation research applications. |
| Applications | Pep-ELISA/WB/IP |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:32000.WB: A 95kDa band was observed in Chicken Embryo Heart atrial and ventricular myocyte lysates (Sabourin et al, ; PMID 21672930). This antibody has been successfully used in WB on Mouse (Mur |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20ยฐC on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | TRPC7 |
| Gene ID | 57113 |
| Uniprot ID | TRPC7_HUMAN |
| Accession Number | NP_065122.1; NP_001161049.1; NP_001161048.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | KLCKSKAKSCEND |
| Specificity | This antibody is expected to cross-react with isoform 1, 2 and 3 (NP_065122.1; NP_001161049.1; NP_001161048.1). |
Additional Info
| Function | Forms a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG). May also be activated by intracellular calcium store depletion. |
| Protein Name | Short Transient Receptor Potential Channel 7Trpc7Transient Receptor Protein 7Trp-7Htrp7 |
| Database Links | Reactome: R-HSA-114508Reactome: R-HSA-139853Reactome: R-HSA-3295583Reactome: R-HSA-418890 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinNucleus Envelope |
| Alternative Antibody Names | Anti-Short Transient Receptor Potential Channel 7 antibodyAnti-Trpc7 antibodyAnti-Transient Receptor Protein 7 antibodyAnti-Trp-7 antibodyAnti-Htrp7 antibodyAnti-TRPC7 antibodyAnti-TRP7 antibody |
Information sourced from Uniprot.org