| Host: | Goat |
| Applications: | Pep-ELISA/WB/IP |
| Reactivity: | Human/Mouse/Rat/Dog/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-TRPC7 (Internal) is suitable for use in ELISA, Western Blot and Immunoprecipitation research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: A 95kDa band was observed in Chicken Embryo Heart atrial and ventricular myocyte lysates (Sabourin et al, ; PMID 21672930). This antibody has been successfully used in WB on Mouse (Mur |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | TRPC7 |
| Gene ID: | 57113 |
| Uniprot ID: | TRPC7_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_065122.1; NP_001161049.1; NP_001161048.1 |
| Specificity: | This antibody is expected to cross-react with isoform 1, 2 and 3 (NP_065122.1; NP_001161049.1; NP_001161048.1). |
| Immunogen Sequence: | KLCKSKAKSCEND |
| Function | Forms a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG). May also be activated by intracellular calcium store depletion. |
| Protein Name | Short Transient Receptor Potential Channel 7Trpc7Transient Receptor Protein 7Trp-7Htrp7 |
| Database Links | Reactome: R-HSA-114508Reactome: R-HSA-139853Reactome: R-HSA-3295583Reactome: R-HSA-418890 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinNucleus Envelope |
| Alternative Antibody Names | Anti-Short Transient Receptor Potential Channel 7 antibodyAnti-Trpc7 antibodyAnti-Transient Receptor Protein 7 antibodyAnti-Trp-7 antibodyAnti-Htrp7 antibodyAnti-TRPC7 antibodyAnti-TRP7 antibody |
Information sourced from Uniprot.org
