Anti-TROVE2 antibody (1-260) (STJ29066)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TROVE2 (1-260) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RO60 |
| Gene ID | 6738 |
| Uniprot ID | RO60_HUMAN |
| Immunogen Region | 1-260 |
| Immunogen Sequence | MEESVNQMQPLNEKQIANSQ DGYVWQVTDMNRLHRFLCFG SEGGTYYIKEQKLGLENAEA LIRLIEDGRGCEVIQEIKSF SQEGRTTKQEPMLFALAICS QCSDISTKQAAFKAVSEVCR IPTHLFTFIQFKKDLKESMK CGMWGRALRKAIADWYNEKG GMALALAVTKYKQRNGWSHK DLLRLSHLKPSSEGLAIVTK YITKGWKEVHELYKEKALSV ETEKLLKYLEAVEKVKRTR |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human TROVE2 (NP_004591.2). |
Additional Info
| Function | RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs. Binds to endogenous Alu retroelements which are induced by type I interferon and stimulate porinflammatory cytokine secretion. Regulates the expression of Alu retroelements as well as inflammatory genes. May play roles in cilia formation and/or maintenance. |
| Protein Name | Rna-Binding Protein Ro6060 Kda Ss-A/Ro Ribonucleoprotein60 Kda Ro Protein60 Kda Ribonucleoprotein RoRornpRo 60 Kda AutoantigenRo60 AutoantigenSjoegren Syndrome Antigen A2Sjoegren Syndrome Type A AntigenSs-ATrove Domain Family Member 2 |
| Database Links | |
| Cellular Localisation | CytoplasmLocalized In Cytoplasmic Mrnp Granules Containing Untranslated Mrnas |
| Alternative Antibody Names | Anti-Rna-Binding Protein Ro60 antibodyAnti-60 Kda Ss-A/Ro Ribonucleoprotein antibodyAnti-60 Kda Ro Protein antibodyAnti-60 Kda Ribonucleoprotein Ro antibodyAnti-Rornp antibodyAnti-Ro 60 Kda Autoantigen antibodyAnti-Ro60 Autoantigen antibodyAnti-Sjoegren Syndrome Antigen A2 antibodyAnti-Sjoegren Syndrome Type A Antigen antibodyAnti-Ss-A antibodyAnti-Trove Domain Family Member 2 antibodyAnti-RO60 antibodyAnti-SSA2 antibodyAnti-TROVE2 antibody |
Information sourced from Uniprot.org