| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TROVE2 (1-260) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RO60 |
| Gene ID: |
6738 |
| Uniprot ID: |
RO60_HUMAN |
| Immunogen Region: |
1-260 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human TROVE2 (NP_004591.2). |
| Immunogen Sequence: |
MEESVNQMQPLNEKQIANSQ DGYVWQVTDMNRLHRFLCFG SEGGTYYIKEQKLGLENAEA LIRLIEDGRGCEVIQEIKSF SQEGRTTKQEPMLFALAICS QCSDISTKQAAFKAVSEVCR IPTHLFTFIQFKKDLKESMK CGMWGRALRKAIADWYNEKG GMALALAVTKYKQRNGWSHK DLLRLSHLKPSSEGLAIVTK YITKGWKEVHELYKEKALSV ETEKLLKYLEAVEKVKRTR |
| Function | RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs. Binds to endogenous Alu retroelements which are induced by type I interferon and stimulate porinflammatory cytokine secretion. Regulates the expression of Alu retroelements as well as inflammatory genes. May play roles in cilia formation and/or maintenance. |
| Protein Name | Rna-Binding Protein Ro6060 Kda Ss-A/Ro Ribonucleoprotein60 Kda Ro Protein60 Kda Ribonucleoprotein RoRornpRo 60 Kda AutoantigenRo60 AutoantigenSjoegren Syndrome Antigen A2Sjoegren Syndrome Type A AntigenSs-ATrove Domain Family Member 2 |
| Cellular Localisation | CytoplasmLocalized In Cytoplasmic Mrnp Granules Containing Untranslated Mrnas |
| Alternative Antibody Names | Anti-Rna-Binding Protein Ro60 antibodyAnti-60 Kda Ss-A/Ro Ribonucleoprotein antibodyAnti-60 Kda Ro Protein antibodyAnti-60 Kda Ribonucleoprotein Ro antibodyAnti-Rornp antibodyAnti-Ro 60 Kda Autoantigen antibodyAnti-Ro60 Autoantigen antibodyAnti-Sjoegren Syndrome Antigen A2 antibodyAnti-Sjoegren Syndrome Type A Antigen antibodyAnti-Ss-A antibodyAnti-Trove Domain Family Member 2 antibodyAnti-RO60 antibodyAnti-SSA2 antibodyAnti-TROVE2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
