Anti-TROVE2 antibody (1-260) (STJ29066)

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STJ29066
£110.50 - £505.50
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Applications:WB/ELISA
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:RO60
Gene ID:6738
Uniprot ID:RO60_HUMAN
Immunogen Region:1-260
Immunogen Sequence:MEESVNQMQPLNEKQIANSQ DGYVWQVTDMNRLHRFLCFG SEGGTYYIKEQKLGLENAEA LIRLIEDGRGCEVIQEIKSF SQEGRTTKQEPMLFALAICS QCSDISTKQAAFKAVSEVCR IPTHLFTFIQFKKDLKESMK CGMWGRALRKAIADWYNEKG GMALALAVTKYKQRNGWSHK DLLRLSHLKPSSEGLAIVTK YITKGWKEVHELYKEKALSV ETEKLLKYLEAVEKVKRTR
Specificity:Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human TROVE2 (NP_004591.2).
Function RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs. Binds to endogenous Alu retroelements which are induced by type I interferon and stimulate porinflammatory cytokine secretion. Regulates the expression of Alu retroelements as well as inflammatory genes. May play roles in cilia formation and/or maintenance.
Protein Name Rna-Binding Protein Ro60
60 Kda Ss-A/Ro Ribonucleoprotein
60 Kda Ro Protein
60 Kda Ribonucleoprotein Ro
Rornp
Ro 60 Kda Autoantigen
Ro60 Autoantigen
Sjoegren Syndrome Antigen A2
Sjoegren Syndrome Type A Antigen
Ss-A
Trove Domain Family Member 2
Database Links
Cellular Localisation Cytoplasm
Localized In Cytoplasmic Mrnp Granules Containing Untranslated Mrnas
Alternative Antibody Names Anti-Rna-Binding Protein Ro60 antibody
Anti-60 Kda Ss-A/Ro Ribonucleoprotein antibody
Anti-60 Kda Ro Protein antibody
Anti-60 Kda Ribonucleoprotein Ro antibody
Anti-Rornp antibody
Anti-Ro 60 Kda Autoantigen antibody
Anti-Ro60 Autoantigen antibody
Anti-Sjoegren Syndrome Antigen A2 antibody
Anti-Sjoegren Syndrome Type A Antigen antibody
Anti-Ss-A antibody
Anti-Trove Domain Family Member 2 antibody
Anti-RO60 antibody
Anti-SSA2 antibody
Anti-TROVE2 antibody

Information sourced from Uniprot.org