Anti-TRMT61A antibody (1-289) (STJ112610)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TRMT61A (1-289) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TRMT61A |
| Gene ID | 115708 |
| Uniprot ID | TRM61_HUMAN |
| Immunogen Region | 1-289 |
| Immunogen Sequence | MSFVAYEELIKEGDTAILSL GHGAMVAVRVQRGAQTQTRH GVLRHSVDLIGRPFGSKVTC GRGGWVYVLHPTPELWTLNL PHRTQILYSTDIALITMMLE LRPGSVVCESGTGSGSVSHA IIRTIAPTGHLHTVEFHQQR AEKAREEFQEHRVGRWVTVR TQDVCRSGFGVSHVADAVFL DIPSPWEAVGHAWDALKVEG GRFCSFSPCIEQVQRTCQAL AARGFSELSTLEVLPQVYN |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-289 of human TRMT61A (NP_689520.2). |
Additional Info
| Function | Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. Catalytic subunit of mRNA N(1)-methyltransferase complex, which mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs: N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries. |
| Protein Name | TrnaAdenine(58-N(1-Methyltransferase Catalytic Subunit Trmt61aMrna Methyladenosine-N(1-Methyltransferase Catalytic Subunit Trmt61aTrna(M1a58-Methyltransferase Subunit Trmt61aTrna(M1a58mtase Subunit Trmt61a |
| Database Links | Reactome: R-HSA-6782315 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Trna antibodyAnti-Adenine(58-N(1-Methyltransferase Catalytic Subunit Trmt61a antibodyAnti-Mrna Methyladenosine-N(1-Methyltransferase Catalytic Subunit Trmt61a antibodyAnti-Trna(M1a58-Methyltransferase Subunit Trmt61a antibodyAnti-Trna(M1a58mtase Subunit Trmt61a antibodyAnti-TRMT61A antibodyAnti-C14orf172 antibodyAnti-TRM61 antibody |
Information sourced from Uniprot.org