Anti-TRMT6 antibody (1-200) (STJ113624)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TRMT6 (1-200) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TRMT6 |
| Gene ID | 51605 |
| Uniprot ID | TRM6_HUMAN |
| Immunogen Region | 1-200 |
| Immunogen Sequence | MEGSGEQPGPQPQHPGDHRI RDGDFVVLKREDVFKAVQVQ RRKKVTFEKQWFYLDNVIGH SYGTAFEVTSGGSLQPKKKR EEPTAETKEAGTDNRNIVDD GKSQKLTQDDIKALKDKGIK GEEIVQQLIENSTTFRDKTE FAQDKYIKKKKKKYEAIITV VKPSTRILSIMYYAREPGKI NHMRYDTLAQMLTLGNIRAG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human TRMT6 (NP_057023.2). |
Additional Info
| Tissue Specificity | Expressed in brain, liver, testis and ovary. |
| Function | Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. Together with the TRMT61A catalytic subunit, part of a mRNA N(1)-methyltransferase complex that mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs: N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries. |
| Protein Name | TrnaAdenine(58-N(1-Methyltransferase Non-Catalytic Subunit Trm6Mrna Methyladenosine-N(1-Methyltransferase Non-Catalytic Subunit Trm6Trna(M1a58-Methyltransferase Subunit Trm6Trna(M1a58mtase Subunit Trm6 |
| Database Links | Reactome: R-HSA-6782315 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Trna antibodyAnti-Adenine(58-N(1-Methyltransferase Non-Catalytic Subunit Trm6 antibodyAnti-Mrna Methyladenosine-N(1-Methyltransferase Non-Catalytic Subunit Trm6 antibodyAnti-Trna(M1a58-Methyltransferase Subunit Trm6 antibodyAnti-Trna(M1a58mtase Subunit Trm6 antibodyAnti-TRMT6 antibodyAnti-KIAA1153 antibodyAnti-TRM6 antibodyAnti-CGI-09 antibody |
Information sourced from Uniprot.org