| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TRMT6 (1-200) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TRMT6 |
| Gene ID: |
51605 |
| Uniprot ID: |
TRM6_HUMAN |
| Immunogen Region: |
1-200 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human TRMT6 (NP_057023.2). |
| Immunogen Sequence: |
MEGSGEQPGPQPQHPGDHRI RDGDFVVLKREDVFKAVQVQ RRKKVTFEKQWFYLDNVIGH SYGTAFEVTSGGSLQPKKKR EEPTAETKEAGTDNRNIVDD GKSQKLTQDDIKALKDKGIK GEEIVQQLIENSTTFRDKTE FAQDKYIKKKKKKYEAIITV VKPSTRILSIMYYAREPGKI NHMRYDTLAQMLTLGNIRAG |
| Tissue Specificity | Expressed in brain, liver, testis and ovary. |
| Function | Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. Together with the TRMT61A catalytic subunit, part of a mRNA N(1)-methyltransferase complex that mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs: N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries. |
| Protein Name | TrnaAdenine(58-N(1-Methyltransferase Non-Catalytic Subunit Trm6Mrna Methyladenosine-N(1-Methyltransferase Non-Catalytic Subunit Trm6Trna(M1a58-Methyltransferase Subunit Trm6Trna(M1a58mtase Subunit Trm6 |
| Database Links | Reactome: R-HSA-6782315 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Trna antibodyAnti-Adenine(58-N(1-Methyltransferase Non-Catalytic Subunit Trm6 antibodyAnti-Mrna Methyladenosine-N(1-Methyltransferase Non-Catalytic Subunit Trm6 antibodyAnti-Trna(M1a58-Methyltransferase Subunit Trm6 antibodyAnti-Trna(M1a58mtase Subunit Trm6 antibodyAnti-TRMT6 antibodyAnti-KIAA1153 antibodyAnti-TRM6 antibodyAnti-CGI-09 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
