Anti-TRMT2A antibody (1-250) (STJ11104340)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal Trna (1-250) antibody for use in WB, IHC-P and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TRMT2A |
| Gene ID | 27037 |
| Uniprot ID | TRM2A_HUMAN |
| Immunogen Region | 1-250 |
| Immunogen Sequence | MSENLDNEGPKPMESCGQES SSALSCPTVSVPPAAPAALE EVEKEGAGAATGPGPQPGLY SYIRDDLFTSEIFKLELQNV PRHASFSDVRRFLGRFGLQP HKTKLFGQPPCAFVTFRSAA ERDKALRVLHGALWKGRPLS VRLARPKADPMARRRRQEGE SEPPVTRVADVVTPLWTVPY AEQLERKQLECEQVLQKLAK EIGSTNRALLPWLLEQRHKH NKACCPLEGVRPSPQQTEY |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human TRMT2A/HTF9C (NP_073564.3). |
Additional Info
| Function | S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the formation of 5-methyl-uridine in tRNAs and some mRNAs. Mainly catalyzes the methylation of uridine at position 54 (m5U54) in cytosolic tRNAs. Also able to mediate the formation of 5-methyl-uridine in some mRNAs. |
| Protein Name | TrnaUracil-5--Methyltransferase Homolog AMrnaUracil-5--Methyltransferase Trmt2a |
| Database Links | |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Trna antibodyAnti-Uracil-5--Methyltransferase Homolog A antibodyAnti-Mrna antibodyAnti-Uracil-5--Methyltransferase Trmt2a antibodyAnti-TRMT2A antibody |
Information sourced from Uniprot.org