| Post Translational Modifications | (Microbial infection) Cleaved between Gln-530 and Ala-531 by the 3C-like proteinase nsp5 from human coronavirus SARS-CoV-2, leading to its inactivation. |
| Function | Dimethylates a single guanine residue at position 26 of most nuclear- and mitochondrial-encoded tRNAs using S-adenosyl-L-methionine as donor of the methyl groups. tRNA guanine(26)-dimethylation is required for redox homeostasis and ensure proper cellular proliferation and oxidative stress survival. |
| Protein Name | TrnaGuanine(26-N(2-DimethyltransferaseTrna 2 -2-Dimethylguanosine-26 MethyltransferaseTrna Methyltransferase 1Htrm1Trna(Guanine-26 -N(2-N(2 MethyltransferaseTrna(M(2 -2g26dimethyltransferase |
| Database Links | Reactome: R-HSA-6782315 |
| Cellular Localisation | Isoform 1: MitochondrionIsoform 3: NucleusCytoplasm |
| Alternative Antibody Names | Anti-Trna antibodyAnti-Guanine(26-N(2-Dimethyltransferase antibodyAnti-Trna 2 -2-Dimethylguanosine-26 Methyltransferase antibodyAnti-Trna Methyltransferase 1 antibodyAnti-Htrm1 antibodyAnti-Trna(Guanine-26 -N(2-N(2 Methyltransferase antibodyAnti-Trna(M(2 -2g26dimethyltransferase antibodyAnti-TRMT1 antibody |
Information sourced from Uniprot.org
