Anti-TRIM60 antibody (1-300) (STJ118408)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TRIM60 (1-300) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TRIM60 |
| Gene ID | 166655 |
| Uniprot ID | TRI60_HUMAN |
| Immunogen Region | 1-300 |
| Immunogen Sequence | MEFVTALVNLQEESSCPICL EYLKDPVTINCGHNFCRSCL SVSWKDLDDTFPCPVCRFCF PYKSFRRNPQLRNLTEIAKQ LQIRRSKRKRQKENAMCEKH NQFLTLFCVKDLEILCTQCS FSTKHQKHYICPIKKAASYH REILEGSLEPLRNNIERVEK VIILQGSKSVELKKKVEYKR EEINSEFEQIRLFLQNEQEM ILRQIQDEEMNILAKLNENL VELSDYVSTLKHLLREVEG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human TRIM60 (NP_689833.1). |
Additional Info
| Function | E3 SUMO-protein ligase that mediates SUMOylation of TAB2 leading to inhibition of NF-kappa-B and MAPK pathways by suppressing the TRAF6/TAB2/TAK1 complex. |
| Protein Name | Tripartite Motif-Containing Protein 60Ring Finger Protein 129Ring Finger Protein 33 |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Tripartite Motif-Containing Protein 60 antibodyAnti-Ring Finger Protein 129 antibodyAnti-Ring Finger Protein 33 antibodyAnti-TRIM60 antibodyAnti-RNF129 antibodyAnti-RNF33 antibody |
Information sourced from Uniprot.org