| Short Description : | Rabbit polyclonal TRIM60 (1-300) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TRIM60 |
| Gene ID: | 166655 |
| Uniprot ID: | TRI60_HUMAN |
| Immunogen Region: | 1-300 |
| Immunogen Sequence: | MEFVTALVNLQEESSCPICL EYLKDPVTINCGHNFCRSCL SVSWKDLDDTFPCPVCRFCF PYKSFRRNPQLRNLTEIAKQ LQIRRSKRKRQKENAMCEKH NQFLTLFCVKDLEILCTQCS FSTKHQKHYICPIKKAASYH REILEGSLEPLRNNIERVEK VIILQGSKSVELKKKVEYKR EEINSEFEQIRLFLQNEQEM ILRQIQDEEMNILAKLNENL VELSDYVSTLKHLLREVEG |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human TRIM60 (NP_689833.1). |
| Function | E3 SUMO-protein ligase that mediates SUMOylation of TAB2 leading to inhibition of NF-kappa-B and MAPK pathways by suppressing the TRAF6/TAB2/TAK1 complex. |
| Protein Name | Tripartite Motif-Containing Protein 60Ring Finger Protein 129Ring Finger Protein 33 |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Tripartite Motif-Containing Protein 60 antibodyAnti-Ring Finger Protein 129 antibodyAnti-Ring Finger Protein 33 antibodyAnti-TRIM60 antibodyAnti-RNF129 antibodyAnti-RNF33 antibody |
Information sourced from Uniprot.org
![Immunofluorescence analysis of HeLa cells using [KO Validated] PRMT2 Rabbit polyclonal antibody (STJ28398). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/101688/389745/STJ28398_1__85710.1713159476.jpg?c=1 "Immunofluorescence analysis of HeLa cells using [KO Validated] PRMT2 Rabbit polyclonal antibody (STJ28398). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution.")
