Anti-TRIM4 antibody (1-280) (STJ118367)

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STJ118367
£110.50 - £505.50
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Short Description :Rabbit polyclonal TRIM4 (1-280) antibody for use in WB, IF, ICC and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IF/ICC/ELISA
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:500-1:1000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:TRIM4
Gene ID:89122
Uniprot ID:TRIM4_HUMAN
Immunogen Region:1-280
Immunogen Sequence:MEAEDIQEELTCPICLDYFQ DPVSIECGHNFCRGCLHRNW APGGGPFPCPECRHPSAPAA LRPNWALARLTEKTQRRRLG PVPPGLCGRHWEPLRLFCED DQRPVCLVCRESQEHQTHAM APIDEAFESYRTGNFDIHVD EWKRRLIRLLLYHFKQEEKL LKSQRNLVAKMKKVMHLQDV EVKNATQWKDKIKSQRMRIS TEFSKLHNFLVEEEDLFLQR LNKEEEETKKKLNENTLKL
Specificity:Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human TRIM4 (NP_148977.2).
Function E3 ubiquitin-protein ligase. Mediates 'Lys-63'-linked polyubiquitination of the innate immune receptor RIGI, this linkage doesn't lead to proteasomal degradation but seems to enhance IFN induction.
Protein Name E3 Ubiquitin-Protein Ligase Trim4
Ring Finger Protein 87
Ring-Type E3 Ubiquitin Transferase Trim4
Tripartite Motif-Containing Protein 4
Database Links Reactome: R-HSA-168928
Reactome: R-HSA-5689896
Reactome: R-HSA-918233
Reactome: R-HSA-933541
Reactome: R-HSA-933542
Reactome: R-HSA-933543
Reactome: R-HSA-936440
Reactome: R-HSA-9705671
Reactome: R-HSA-983168
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-E3 Ubiquitin-Protein Ligase Trim4 antibody
Anti-Ring Finger Protein 87 antibody
Anti-Ring-Type E3 Ubiquitin Transferase Trim4 antibody
Anti-Tripartite Motif-Containing Protein 4 antibody
Anti-TRIM4 antibody
Anti-RNF87 antibody

Information sourced from Uniprot.org