Anti-TRIM4 antibody (1-280) (STJ118367)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TRIM4 (1-280) antibody for use in WB, IF, ICC and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TRIM4 |
| Gene ID | 89122 |
| Uniprot ID | TRIM4_HUMAN |
| Immunogen Region | 1-280 |
| Immunogen Sequence | MEAEDIQEELTCPICLDYFQ DPVSIECGHNFCRGCLHRNW APGGGPFPCPECRHPSAPAA LRPNWALARLTEKTQRRRLG PVPPGLCGRHWEPLRLFCED DQRPVCLVCRESQEHQTHAM APIDEAFESYRTGNFDIHVD EWKRRLIRLLLYHFKQEEKL LKSQRNLVAKMKKVMHLQDV EVKNATQWKDKIKSQRMRIS TEFSKLHNFLVEEEDLFLQR LNKEEEETKKKLNENTLKL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human TRIM4 (NP_148977.2). |
Additional Info
| Function | E3 ubiquitin-protein ligase. Mediates 'Lys-63'-linked polyubiquitination of the innate immune receptor RIGI, this linkage doesn't lead to proteasomal degradation but seems to enhance IFN induction. |
| Protein Name | E3 Ubiquitin-Protein Ligase Trim4Ring Finger Protein 87Ring-Type E3 Ubiquitin Transferase Trim4Tripartite Motif-Containing Protein 4 |
| Database Links | Reactome: R-HSA-168928Reactome: R-HSA-5689896Reactome: R-HSA-918233Reactome: R-HSA-933541Reactome: R-HSA-933542Reactome: R-HSA-933543Reactome: R-HSA-936440Reactome: R-HSA-9705671Reactome: R-HSA-983168 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Trim4 antibodyAnti-Ring Finger Protein 87 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Trim4 antibodyAnti-Tripartite Motif-Containing Protein 4 antibodyAnti-TRIM4 antibodyAnti-RNF87 antibody |
Information sourced from Uniprot.org