• Immunohistochemistry analysis of paraffin-embedded human testis, using TRIM16 Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-TRIM16 antibody (31-80 aa) (STJ96100)

SKU:
STJ96100

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Tripartite motif-containing protein 16 (31-80 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TRIM16
Gene ID: 10626
Uniprot ID: TRI16_HUMAN
Immunogen Region: 31-80 aa
Specificity: TRIM16 Polyclonal Antibody detects endogenous levels of TRIM16 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human TRIM16 at the amino acid range 31-80
Post Translational Modifications Phosphorylated by ULK1. Auto-ubiquitinates via its B-Boxes.
Function E3 ubiquitin ligase that plays an essential role in the organization of autophagic response and ubiquitination upon lysosomal and phagosomal damages. Plays a role in the stress-induced biogenesis and degradation of protein aggresomes by regulating the p62-KEAP1-NRF2 signaling and particularly by modulating the ubiquitination levels and thus stability of NRF2. Acts as a scaffold protein and facilitates autophagic degradation of protein aggregates by interacting with p62/SQSTM, ATG16L1 and LC3B/MAP1LC3B. In turn, protects the cell against oxidative stress-induced cell death as a consequence of endomembrane damage.
Protein Name Tripartite Motif-Containing Protein 16
E3 Ubiquitin-Protein Ligase Trim16
Estrogen-Responsive B Box Protein
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Tripartite Motif-Containing Protein 16 antibody
Anti-E3 Ubiquitin-Protein Ligase Trim16 antibody
Anti-Estrogen-Responsive B Box Protein antibody
Anti-TRIM16 antibody
Anti-EBBP antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance