| Host: | Rabbit |
| Applications: | WB/IHC-P/IP/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S7MR |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 IHC-P:1:50-1:200IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TPT1 |
| Gene ID: | 7178 |
| Uniprot ID: | TCTP_HUMAN |
| Immunogen Region: | 1-100 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TCTP/TPT1 (P13693). |
| Immunogen Sequence: | MIIYRDLISHDEMFSDIYKI REIADGLCLEVEGKMVSRTE GNIDDSLIGGNASAEGPEGE GTESTVITGVDIVMNHHLQE TSFTKEAYKKYIKDYMKSIK |
| Tissue Specificity | Found in several healthy and tumoral cells including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas, and lymphomas. It cannot be detected in kidney and renal cell carcinoma (RCC). Expressed in placenta and prostate. |
| Function | Involved in calcium binding and microtubule stabilization. Acts as a negative regulator of TSC22D1-mediated apoptosis, via interaction with and destabilization of TSC22D1 protein. |
| Protein Name | Translationally-Controlled Tumor ProteinTctpFortilinHistamine-Releasing FactorHrfP23 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Translationally-Controlled Tumor Protein antibodyAnti-Tctp antibodyAnti-Fortilin antibodyAnti-Histamine-Releasing Factor antibodyAnti-Hrf antibodyAnti-P23 antibodyAnti-TPT1 antibody |
Information sourced from Uniprot.org